Report an Adverse Event using the VAERS online form or the downloadable PDF. It isn't clear how long these effects might last. de Terreros Caro GG, Daz SG, Al MP, Gimeno MM. RH: carried out the searched publications, classified the documents, and wrote the manuscript draft. https://www.cdc.gov/coronavirus/2019-ncov/vaccines/recommendations.html. Immunopathologia Persa. Althoughvaccines are now considered the best way to achieve collective safety and control mortality, due to the critical situation, these vaccines have been issued the emergency use licenses andsome of theirpotentialsubsequence side effects have been overlooked. 2021;385(8):7208. Herpes zoster following COVID-19 vaccine: a report of three cases. Kadyrova I, Yegorov S, Negmetzhanov B, Kolesnikova Y, Kolesnichenko S, Korshukov I, Baiken Y, Matkarimov B, Miller MS, Hortelano GH. Acute disseminated encephalomyelitis-like presentation after an inactivated coronavirus vaccine. 2021;9(9):1008. Acute transverse myelitis after inactivated COVID-19 vaccine. If these side effects occur, they should go away in a few days. This virus is known to cause widespread lung infection and hypoxia [1]. These cookies may also be used for advertising purposes by these third parties. Understand the possible symptoms and risk factors for post-COVID-19 syndrome. 241(d); 5 U.S.C. Wichova H, Miller ME, Derebery MJ. Due to the leakage of these genetic materials and their binding to factor 4 platelet, autoimmunity develops [29]. RELATED: Most COVID Patients Did This Before Getting Sick 5 COVID-19: Evaluation and management of adults following acute viral illness. Coronavirus vaccinations per country over time One model suggests that a combination of the slow vaccine rollout, the decrease in social distancing seen, and the spread of much more contagious forms of the virus could result in 300,000 more deaths in the U.S. over the next three months. Correspondence to Neurological complications of COVID-19: Guillain-Barre syndrome following Pfizer COVID-19 vaccine. Loza AMM, Holroyd KB, Johnson SA, Pilgrim DM, Amato AA. Front Immunol. Obermann M, Krasniqi M, Ewers N, Fayad J, Haeberle U. Bells palsy following COVID-19 vaccination with high CSF antibody response. Feelings of having a fast-beating, fluttering or pounding heartbeat, Severe or persistent headaches or blurred vision, Easy bruising or tiny blood spots under the skin near the injection site. Each of the five sites reported all anxiety-related events to VAERS; reports for each event were reviewed by CDC. 2022;269(1):558. Bjrnstad-Tuveng TH, Rudjord A, Anker P. Fatal cerebral haemorrhage after COVID-19 vaccine. Venous sinus thrombosis and cerebral hemorrhage are more common in women between the ages of 30 and 50 than in men (Table 2) [8]. Autoimmun Rev. Suggested citation for this article: Hause AM, Gee J, Johnson T, et al. Coronavirus disease 2019 and cardiovascular complications: Focused clinical review. Rehabilitation after COVID-19 - Related information, Post-COVID Recovery - Related information, Post-COVID-19 syndrome could be a long haul (podcast) - Related information, Post-COVID-19 syndrome could be a long haul (podcast), Post-COVID conditions - Related information. The information you provide and any test results will help your health care provider come up with a treatment plan. However, anyone who gets COVID-19 can have long-term effects, including people with no symptoms or mild illness with COVID-19. 2021;96(8):E3013. Syncope after Janssen COVID-19 vaccination was reported to VAERS (8.2 episodes per 100,000 doses). J Neurol. PubMedGoogle Scholar. Neurologia (Barc, Ed impr). S Vaccine. As reported in both studies, the majority of reactions beyond a sore arm happen . On April 7, 2021, after 5 weeks use of the Janssen COVID-19 vaccine under the Food and Drug Administration (FDA) Emergency Use Authorization (EUA), CDC received reports of clusters of anxiety-related events after administration of Janssen COVID-19 vaccine from five mass vaccination sites, all in different states. Malhotra HS, Gupta P, Prabhu V, Garg RK, Dandu H, Agarwal V. COVID-19 vaccination-associated myelitis. The problem occurs more often in adolescents (teens) and young adults, and in males. 2021. https://doi.org/10.1155/2021/3619131. JAAD Case Rep. 2021;12:589. Learn more: Vaccines, Boosters & Additional Doses | Testing | Patient Care | Visitor Guidelines | Coronavirus. 2021. https://doi.org/10.7759/cureus.13426. headache. Department of Biology, Faculty of Sciences, Shahid Bahonar University of Kerman, P.O.Box 76135-133, Kerman, Islamic Republic of Iran, Immunoregulation Research Center, Shahed University, Tehran, Islamic Republic of Iran, You can also search for this author in 2022; doi:10.15585/mmwr.mm7121e1. Side-effects with the COVID-19 vaccines are never pleasant and the hesitancy of developing the reactions have scared many into getting jabbed. Cureus. Four of the five sites (all except site E) administered Janssen vaccine for the first time on the day these clusters were reported. Seek medical attention right away if, within a few days of receiving the second injection of an mRNA COVID-19 vaccination (Pfizer-BioNTech, Moderna), you or your child experience: Having COVID-19 can also cause heart problems. More than half said they experienced a sore arm, fatigue or headache. 2021;11(4):285. That is the most troubling unknown for me." Weighing the odds The most important and common complicationsare cerebrovasculardisorders including cerebral venous sinus thrombosis, transient ischemic attack, intracerebral hemorrhage, ischemic stroke, and demyelinatingdisorders including transverse myelitis, first manifestation of MS, and neuromyelitis optica. It was such a strange, unfamiliar sensation that I didn't realize what was happening. In addition, skin blisters have been observed in the ear area, leading us to hypothesize that reactivation of VZV could be a cause for RHS as well as Bell's palsy [71]. Article This content does not have an English version. A single copy of these materials may be reprinted for noncommercial personal use only. Syncope and seizures following human papillomavirus vaccination: a retrospective case series. Keywords used for this search included COVID-19, SARS-CoV-2, vaccination, side effects, complications, vascular thrombosis, thrombocytopenia, myelitis, demyelination, and all kind of mRNA vaccines, Adenovirus vaccine, Pfizer, AstraZeneca, Johnson & Johnson, Moderna, Sinovac, Sinopharm, Sputnik, and Covaxin. These symptoms do not mean you are sick. The Food and Drug Administration sees a possible risk of Guillain-Barre syndrome with Pfizer 's RSV vaccine for older adults and has asked the company to conduct a safety study if the shot is . J Am Acad Dermatol. The Food and Drug Administration warned on Monday that Johnson & Johnson's coronavirus vaccine can lead to an increased risk of a rare neurological condition known as Guillain-Barr syndrome . Etemadifar M, Sigari AA, Sedaghat N, Salari M, Nouri H. Acute relapse and poor immunization following COVID-19 vaccination in a rituximab-treated multiple sclerosis patient. According to these reports, vaccination can have an adverse event, especially on nervous system. There are four major strategies for producing COVID-19 vaccines, including nucleic acid-based vaccine (DNAmRNA), viral vector (replicationnon-replication), live inactivated (or attenuated) virus, and protein (spike protein or its subunits). A third reported fever or chills, and about a fifth said they were nauseous. In addition, in mass vaccination situations, an anxiety-related event witnessed by others on-site or reported through media coverage might provoke additional anxiety-induced episodes (4). Developed PTSD as a result as confirmed by several long-term doctors and therapists and my psychiatrist (I say this because people always try to claim that I don't actually have trauma regardless of official diagnosis). The most commonly reported side effects were: Fever Headache Fatigue (tiredness) Pain at the injection site Helpful tips to relieve side effects Adults To relieve pain or swelling on the arm where you got the shot: Apply a clean, cool, wet washcloth over the area. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). CAS The chances of any of these side effects occurring after vaccination differ according to the specific vaccine. February 27, 2021 / 3:13 PM / CBS Colorado. Acta Neurol Belg. Acute abducens nerve palsy following COVID-19 vaccination. 2021;42(9): e1213. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Bourguignon A, Arnold DM, Warkentin TE, Smith JW, Pannu T, Shrum JM, Al Maqrashi ZA, Shroff A, Lessard M-C, Blais N. Adjunct immune globulin for vaccine-induced immune thrombotic thrombocytopenia. Seyed Ahadi M, Ghadiri F, Naser Moghadasi A. They signal that your immune system is responding to the shot and building up protection against the coronavirus. That is the most troubling unknown for me." 2021;111:21926. A review of neurological side effects of COVID-19 vaccination, https://doi.org/10.1186/s40001-023-00992-0, https://doi.org/10.1007/s10072-021-05662-9, https://doi.org/10.1038/s41598-022-17514-3, https://doi.org/10.1007/s13760-021-01775-2, https://doi.org/10.9734/ijmpcr/2021/v14i130124, https://doi.org/10.1007/s12024-021-00440-7, https://doi.org/10.1016/j.nrleng.2021.05.002, https://doi.org/10.6061/clinics/2021/e3286, https://doi.org/10.1080/14992027.2021.1931969, https://doi.org/10.1136/postgradmedj-2021-141022, https://doi.org/10.1007/s00415-021-10780-7, https://doi.org/10.1016/j.nrleng.2021.04.002, http://creativecommons.org/licenses/by/4.0/, http://creativecommons.org/publicdomain/zero/1.0/. All authors read and approved the final manuscript. MMWR Morb Mortal Wkly Rep 2021;70:6516. These ongoing health problems are sometimes called post-COVID-19 syndrome, post-COVID conditions, long COVID-19, long-haul COVID-19, and post acute sequelae of SARS COV-2 infection (PASC). Finsterer J, Scorza FA, Scorza CA. Ideggyogyaszati Szemle. To compare the occurrence of these events with those reported after receipt of other vaccines, reports of syncopal events after influenza vaccine administered in the 201920 influenza season were also reviewed. Cite this article. For these two-shot vaccinations: After getting an additional shot of a COVID-19 vaccine, you might experience side effects similar to those after your second dose of the vaccine. Cephalalgia. Ozgen Kenangil G, Ari BC, Guler C, Demir MK. 2021;114(7):5312. The Covid-19 Vaccine Safety Technical (VaST) Work Group confirmed "data available to date suggest likely association" of myocarditis and pericarditis in people who get the Pfizer and Moderna jabs. A panel of experts at the virtual American Academy of Allergy, Asthma and Immunology Annual Meeting highlighted current evidence on allergic reactions to available COVID-19 vaccines and how to. All HTML versions of MMWR articles are generated from final proofs through an automated process. Chills and swollen lymph nodes can also occur. Anxiety, panic attacks, and COVID-19 can share symptoms, including chills and shortness of breath. Journal of Hypertension. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. In this case, too, the known mechanism is the induction of autoimmunity by molecular mimicry. Acute transverse myelitis following COVID-19 vaccination. Br Med J Publ Gr. invader and attacks it with immune cells, the weapons it would use against any virus or . Chills and swollen lymph nodes can also occur. medRxiv. Parrino D, Frosolini A, Gallo C, De Siati RD, Spinato G, de Filippis C. Tinnitus following COVID-19 vaccination: report of three cases. Psychologists say people with serious COVID-19 cases may be at risk for. Views equals page views plus PDF downloads, US case reports of cerebral venous sinus thrombosis with thrombocytopenia after Ad26.COV2.S vaccinationMarch 2 to April 21, 2021external icon. Vegezzi E, Ravaglia S, Buongarzone G, Bini P, Diamanti L, Gastaldi M, Prunetti P, Rognone E, Marchioni E. Acute myelitis and ChAdOx1 nCoV-19 vaccine: casual or causal association? Amyotrophic neuralgia secondary to Vaxzevria (AstraZeneca) COVID-19 vaccine. McLean P, Trefts L. Transverse myelitis 48 hours after the administration of an mRNA COVID 19 vaccine. https://www.cdc.gov/coronavirus/2019-ncov/long-term-effects.html. COV2.S vaccination. Women ages 30-49 years, especially, should be aware of the increased risk of this rare adverse event and should know that other COVID-19 vaccines are available. VAERS reports are limited by the information provided by the reporter and might be incomplete, although those missing information regarding the time of vaccination or the time of the event were not included. Bonifacio GB, Patel D, Cook S, Purcaru E, Couzins M, Domjan J, Ryan S, Alareed A, Tuohy O, Slaght S. Bilateral facial weakness with paraesthesia variant of Guillain-Barr syndrome following Vaxzevria COVID-19 vaccine. Some patients and survivors say the experience has triggered panic attacks and debilitating anxiety for the first time. VAERS is a national passive surveillance system that monitors adverse events after all vaccinations (1). J Neurol. You might run a fever and experience body aches, headaches and tiredness for a day or two. 2021. https://doi.org/10.1007/s10072-021-05662-9. Their concern regarding vaccines' efficacy and side effects. Department of Health and Human Services. COVID-19 vaccines can cause mild side effects after the first or second dose, including: Pain, redness or swelling where the shot was given Fever Fatigue Headache Muscle pain Chills Joint pain Nausea and vomiting Swollen lymph nodes Feeling unwell Most side effects go away in a few days. Gao J-J, Tseng H-P, Lin C-L, Shiu J-S, Lee M-H, Liu C-H. Cureus. . 2021;70(9):9313. Vaccine viral antigens activate platelets or indirectly cause blood to clot by activating complement pathways and increasing thrombin production. All information these cookies collect is aggregated and therefore anonymous. In nucleic acid and adenovirus-based vaccines, fragments of the virus mRNA or genome enter human cells and induce the production of viral proteins [3]. Among the 653 VAERS reports of syncope, 327 (50%) occurred in women. Indian J Ophthalmol. Ann Med Surg. Approximately one half of reports to VAERS of syncope after Janssen COVID-19 vaccination were for persons in the youngest age group (1829 years) recommended for vaccination. Garca-Azorn D, Do TP, Gantenbein AR, Hansen JM, Souza MNP, Obermann M, Pohl H, Schankin CJ, Schytz HW, Sinclair A. 2021. https://doi.org/10.1136/bmj.n1786. These include anaphylaxis, a severe reaction . Centers for Disease Control and Prevention. i had been worried about it beforehand but not to the point where i had an attack. Accessed May 24, 2022. Stratton K, Ford A, Rusch E, Clayton EW, eds. Google Scholar. Syncope, a common anxiety-related event reported by the five mass vaccination sites, has specific MedDRA preferred terms (syncope and syncope vasovagal) and was the focus of this follow-up investigation. ), or your upcoming vacation. Ramsay Hunt syndrome following COVID-19 vaccination. Acute transverse myelitis associated with COVID-19 vaccine: a case report. Institute of Medicine of the National Academies. 2021;14(6): e243629. Other types of side effects from the coronavirus vaccines are not unusual. 45 C.F.R. Antonio Crespo Burillo J, Martnez CL, Arguedas CG, Pueyo FJM. Who Had Serious Side Effects from Covid 19 Vaccine? To hear Shawn Skelton and her fiance tell it, the uncontrollable shaking and tongue spasms she suffered days after taking the Moderna COVID-19 vaccine could only be a. The Lancet. QJM: An Int J Med. Watad A, De Marco G, Mahajna H, Druyan A, Eltity M, Hijazi N, Haddad A, Elias M, Zisman D, Naffaa ME. Pagenkopf C, Sdmeyer M. A case of longitudinally extensive transverse myelitis following vaccination against Covid-19. We don't know why that is, how long these symptoms will last or if there are effective ways to treat them. I truly believe this is a side effect of the vaccine. You might have other tests or procedures, such as chest X-rays, based on your symptoms. 2021;202:1823. Post COVID-19 vaccination-associated neurological complications. 2021. https://doi.org/10.6061/clinics/2021/e3286. The first and most common systemic side effect of COVID-19 vaccines is headache, which is mild to severe and is felt in the frontal area of the head. https://www.cdc.gov/mis/index.html. Cureus. Case Rep Infect Dis. Efficacy and side effects of Sputnik V, Sinopharm and AstraZeneca vaccines to stop COVID-19; a review and discussion. 2022;362: 577765. 2021;24: e01143. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. First, VAERS is a passive surveillance reporting system and subject to underreporting (1). Wait -- could I have. As a follow-up to these interviews, CDC analyzed reports of syncope shortly after receipt of Janssen COVID-19 vaccine to the Vaccine Adverse Event Reporting System (VAERS), the vaccine safety monitoring program managed by CDC and FDA. World J Clin Cases. George G, Friedman KD, Curtis BR, Lind SE. 2021. https://doi.org/10.1007/s12024-021-00440-7. Due to potential blood clots following administration of the Johnson & Johnson vaccine, the CDC updated its recommendations in December 2021. These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. The vast majority of myocarditis or pericarditis cases are mild and resolve quickly. Romn GC, Gracia F, Torres A, Palacios A, Gracia K, Harris D. Acute transverse myelitis (ATM): clinical review of 43 patients with COVID-19-associated ATM and 3 post-vaccination ATM serious adverse events with the ChAdOx1 nCoV-19 vaccine (AZD1222). 2021;90(2):3158. Get information and updates from Johns Hopkins Medicine. An anxiety-related event was defined as any of the following occurring in a person during the 15-minute postvaccination observation period at any of the five sites reporting these clusters: tachycardia (rapid heart rate), hyperventilation (rapid breathing), dyspnea (difficulty breathing), chest pain, paresthesia (numbness or tingling), light-headedness, hypotension (low blood pressure), headache, pallor, or syncope (2). Dutta S, Kaur R, Charan J, Bhardwaj P, Ambwani SR, Babu S, Goyal JP, Haque M. Analysis of neurological adverse events reported in VigiBase from COVID-19 vaccines. A virus that was much more contagious than SARS Covid-1 and spread to different parts of the world in a short time. PubMed Central Khayat-Khoei M, Bhattacharyya S, Katz J, Harrison D, Tauhid S, Bruso P, Houtchens MK, Edwards KR, Bakshi R. COVID-19 mRNA vaccination leading to CNS inflammation: a case series. Sore throat Congestion/runny nose Loss of smell or taste Nausea Diarrhea The virus can lead to pneumonia, respiratory failure, heart problems, liver problems, septic shock, and death. Waheed W, Carey ME, Tandan SR, Tandan R. Post COVID-19 vaccine small fiber neuropathy. New Engl J Med. Herein, we have provided a comprehensive review of documents reporting neurological side effects of COVID-19 vaccines in international databases from 2020 to 2022 and discussed neurological disorders possibly caused by vaccination. J Neuroimmunol. Nayere Askari. Inflammation and problems with the immune system can also happen. Ahmed SH, Waseem S, Shaikh TG, Qadir NA, Siddiqui SA, Ullah I, Waris A, Yousaf Z. SARS-CoV-2 vaccine-associated-tinnitus: a review. Most VAERS reports of syncope are for children aged 1118 years (62%), followed by adults aged 1949 years (25%) (6). Fatigue. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. Vaccine 2018;36:299305. Anxiety-related events, including syncope, can occur immediately after vaccination with any vaccine and might be caused by anxiety about receiving an injection (3). To further investigate these cases, CDC interviewed vaccination site staff members to gather additional information about the reported events and vaccination site practices. Symptoms of a panic attack may include: Pounding heart Sweating Trembling or shaking Shortness of breath Sense of choking Nausea or belly pain Dizziness or lightheadedness Feeling unreal or disconnected from oneself Fear of losing control Fear of "going crazy" or dying Numbness Chills or hot flashes SSRN. Neurol Sci. Post-COVID-19 syndrome involves a variety of new, returning or ongoing symptoms that people experience more than four weeks after getting COVID-19. 2021;358: 577606. 2021;121(4):108991. The CDC noted that the two mRNA vaccines, from Pfizer and Moderna, are preferred over the Johnson & Johnson vaccine, which remains available for those who prefer it and for use in certain circumstances. Part of On April 30, 2021, this report was posted online as an MMWR Early Release. This conversion might result in character translation or format errors in the HTML version. nausea and vomiting. One hundred twenty-three (19%) reports indicated that the recipient had a history of syncope associated with receiving injections or needle aversion. 2021;22(1):15. Sixteen (27%) reports indicated that the patient had received more than one vaccine immediately before the syncopal episode. People with severe symptoms of COVID-19 often need to be treated in a hospital intensive care unit. The knock-on effects coronavirus is having on people's mental health is also a likely cause for the rise. BMJ Case Reports CP. Postgrad Med J. In connection with brain disorders, the possible mechanism is the entry of inflammatory mediators secreted by peripheral blood cells into the brain and the destruction of myelin and axonal degeneration. There have been many reports of the Pfizer vaccine being associated with olfactory [66], visual [67], auditory [68, 69], and sometimes abducens nerve palsy. Her PCP thought she was having a panic attack and gave her Xanax. All COVID-19 vaccine recipients should be observed for at least 15 minutes after vaccination for anxiety-related and other events (e.g., anaphylaxis or immediate allergic reaction) occurring shortly after vaccination. Increased awareness of anxiety-related events after vaccination will enable vaccination providers to make an informed decision about continuing vaccination. For the vast majority of people already vaccinated in the U.S. for COVID-19, the side effects, if any, have been mild. Thromb Res. My fourth idea is that this is a result of fever which can cause delirium, breaks of . headache. California Privacy Statement, Myocarditis is more likely to occur as a result of COVID-19 infection than as a side effect of the vaccines. Clinics. Geneva, Switzerland: World Health Organization; 2019. Google Scholar. The two main mechanisms, ectopic immune reactions, and molecular mimicry, have been proposed for the pathogenicity of vaccines and how these complications occur. Long COVID or post-COVID conditions. Repajic M, Lai XL, Xu P, Liu A. Bells Palsy after second dose of Pfizer COVID-19 vaccination in a patient with history of recurrent Bells palsy. Brain Commun. Clin Neurol Neurosurg. Supportive care included placing the person supine and offering hydration and food. The findings in this report are subject to at least three limitations. https://covid19.who.int/mapFilter=deaths. Signs and symptoms in VAERS reports are coded using the Medical Dictionary for Regulatory Activities (MedDRA) preferred terms. Neuroimmunology Reports. The median age of persons with syncope after Janssen COVID-19 vaccination was 30 years (range=1882 years). Its helpful to understand side effects before you get a COVID-19 vaccine. If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance. 2021;208: 106839. QJM: An Int J Med. Complications usually appear within one day to 1month after injection and are usually acute, transient, and self-limiting, but in severe cases lead to hospitalization and intensive care [8]. 2021;4: 100098. COV2. Multisystem inflammatory syndrome (MIS). 2021;3(3):169. 2021. https://doi.org/10.1002/alr.22809. Am J Hematol. Vaccines. 2021. https://doi.org/10.1111/bjh.17619. The symptoms usually peak in about ten minutes and then begin to subside. If you have never had COVID-19, you may notice more side effects after the second dose than after the first dose. Ogbebor O, Seth H, Min Z, Bhanot N. Guillain-Barr syndrome following the first dose of SARS-CoV-2 vaccine: a temporal occurrence, not a causal association. Ramdeny S, Lang A, Al-Izzi S, Hung A, Anwar I, Kumar P. Management of a patient with a rare congenital limb malformation syndrome after SARS-CoV-2 vaccine-induced thrombosis and thrombocytopenia (VITT). Malik B, Kalantary A, Rikabi K, Kunadi A. Baldelli L, Amore G, Montini A, Panzera I, Rossi S, Cortelli P, Guarino M, Rinaldi R, DAngelo R. Hyperacute reversible encephalopathy related to cytokine storm following COVID-19 vaccine. Delayed headache after COVID-19 vaccination: a red flag for vaccine induced cerebral venous thrombosis. The majority -- 61% -- were women, the median age was 36 years and 20% of the patients told vaccination site staff they had a history of fainting associated with receiving injections or an aversion to needles. This will affect how neurons function and cause the infected to be more susceptible to anxiety and depression. Washington, DC: The National Academies Press; 2012. 2021;67: 102540. RT @FearDept: New study shows artificial sweetener "linked to blood clotting, stroke, heart attack and death" -- the four most frequently reported severe side effects of our COVID vaccines. Most people who get coronavirus disease 2019 (COVID-19) recover within a few weeks. Many have suffered chronic fatigue, chest pain, shortness of breath and brain fog months after their infection. Saving Lives, Protecting People, US case reports of cerebral venous sinus thrombosis with thrombocytopenia after Ad26.COV2.S vaccinationMarch 2 to April 21, 2021, https://www.meddra.org/how-to-use/basics/hierarchy, https://www.cdc.gov/flu/fluvaxview/coverage-1920estimates.htm, https://www.cdc.gov/coronavirus/2019-ncov/vaccines/recommendations.html, https://www.cdc.gov/vaccines/covid-19/info-by-product/clinical-considerations.html, https://doi.org/10.1016/j.vaccine.2015.07.035, https://www.who.int/publications/i/item/10665330277, https://doi.org/10.1016/j.vaccine.2017.11.017, https://doi.org/10.5694/j.1326-5377.2011.tb04138.x, Centers for Disease Control and Prevention, U.S. Department of Health & Human Services, Cases per 1,000 vaccinated, total (per day), Reported history of anxiety related to needles or medical visits. It is noteworthy that rare and scattered reports have been published on the side effects of Sinopharm and other inactivated virus-based vaccines (Table 1). Masks are required inside all of our care facilities, COVID-19 testing locations on Maryland.gov, Coronavirus Symptoms: Frequently Asked Questions. fever or chills. COVID-19 vaccination also affects the cranial and peripheral nerves and causes side effects such as Bell's palsy (facial nerve palsy7 cranial nerve), abducens nerve palsy (lateral rectus ocular muscle nerve palsy6 cranial nerve), impaired vision, olfactory, hearing, GuillainBarre syndrome (GBS), small fiber neuropathy, ParsonageTurner syndrome, and also herpes zoster. Sudden onset of myelitis after COVID-19 vaccination: an under-recognized severe rare adverse event. Recommendations for observation after COVID-19 vaccine administration are available at https://www.cdc.gov/vaccines/covid-19/info-by-product/clinical-considerations.html.